In most cases, the answer is simple: Polyphenols such as xanthohumol, curcumin, quercetin, and resveratrol<\/strong> are among the most extensively studied compounds with antioxidant potential and support for physiological balance.<\/p> At the same time, they share a key limitation: In practice, this means:<\/p> <\/p> Our formulations were analyzed using Dynamic Light Scattering (DLS)<\/strong>, a method that determines the actual particle size in solution.<\/p> You can read more about the underlying mechanism here: Below are the actual results of the laboratory analysis (DLS):<\/strong><\/p> DLS (Dynamic Light Scattering) analysis results for xanthohumol nanoemulsion – average particle size: 48.21 nm, PdI: 0.206. Quality result: good. <\/em><\/p> Dynamic Light Scattering (DLS) test results for a xanthohumol nanoemulsion developed by Green Hemp Poland show:<\/p> The following parameters were obtained:<\/p> The technological process includes controlled homogenization and stabilization of the lipid system, allowing the creation of a stable nanoemulsion with reproducible parameters.<\/p> Achieving the correct particle size is only the first step. The described xanthohumol formulation is also available as a finished product, prepared to order using liposomal nanoemulsion technology: One of the main challenges in nanoemulsion technology is not only achieving the desired particle size, but also maintaining stability over time<\/strong>.<\/p> The system was analyzed using the Turbiscan Stability Index (TSI)<\/strong>, which evaluates destabilization kinetics and structural changes in the formulation.<\/p> Stability test results:<\/strong><\/p> Nanoemulsion Stability Study (TSI – Turbiscan Stability Index) – analysis of system changes over time.<\/em><\/p> Interpretation:<\/strong><\/p> <\/p> System stability is a key factor influencing both the repeatability of performance and the quality of the final product.<\/p> The nanoemulsions are designed for sublingual administration<\/strong>, which significantly changes how active compounds are delivered in the body:<\/p> <\/p> Combined with a particle size of ~50 nm, this can significantly enhance the efficiency of active compound utilization.<\/p> A more detailed explanation of bioavailability mechanisms can be found here: Green Hemp Poland formulations are developed with the goal of combining multiple polyphenols within a single liposomal system.<\/p> Currently, we work on individual compounds separately, optimizing:<\/p> <\/p> In later stages, more complex formulations are planned, combining:<\/p> <\/p> This approach allows for full control over each component, and in the next step, enables the development of synergistic systems.<\/p> The obtained parameters (~48 nm \/ PdI ~0.2<\/strong>) and stability results confirm a high level of technological precision and formulation quality.<\/p> This reflects the direction of modern supplementation:<\/p> not by increasing the dose, but by optimizing the delivery system.<\/strong><\/p> The technology described in this article is applied in specific formulations developed by Green Hemp Poland.<\/p> Explore available products: See collaboration and production opportunities: Green Hemp Poland<\/strong> <\/p> If this topic is of interest to you – leave your email.<\/strong><\/p>
it\u2019s not about the dose \u2014 it\u2019s about bioavailability<\/strong>.<\/p>The problem: limited bioavailability of polyphenols<\/h2>
very low water solubility (hydrophobic nature).<\/strong><\/p>Solution: liposomal nanoemulsion ~50 nm (DLS)<\/h2>
What are liposomes and how they work<\/a><\/strong><\/p>![\"Dynamic](\"https:\/\/liposomalherb.com\/wp-content\/uploads\/2026\/04\/nanoemulsja-liposomalna-dls-48nm-xantohumol-green-hemp-1024x946.jpeg\")
<\/figure>
Particle size below 50 nm indicates high dispersion and improved potential for interaction with biological systems.<\/li>\n\n
A low polydispersity index confirms good homogeneity and stability of the formulation.<\/li>\n\n
The formulation is based exclusively on natural phospholipids, without synthetic emulsifiers.<\/li><\/ul>
The key factor is whether the system remains stable over time.<\/p>
Xanthohumol liposomal<\/a><\/strong><\/p>Stability of nanoemulsion over time<\/h2>
![\"Results](\"https:\/\/liposomalherb.com\/wp-content\/uploads\/2026\/04\/nanoemulsja-stabilnosc-tsi-turbiscan-green-hemp-1024x690.jpeg\")
<\/figure>Why sublingual administration?<\/h2>
Liposomal curcumin \u2013 bioavailability, effects and comparison with infusions<\/a><\/strong><\/p>Synergy of ingredients<\/h2>
Summary<\/h2>
Formulations and products<\/a><\/strong><\/p>
LiposomeFactory<\/a><\/strong><\/p>
Hubert Pyrgiel
Innovation based on technology and nature.<\/em><\/p>